Goitre

Shopping on line can be easy, simple and save you lots of money. It can also take a lot of your time, frustrate you, and result in unwanted purchases. Now the same can be said for regular high street shopping, but with the vast opportunity presented by the Internet it will pay you to spend a few minutes reading this and understanding how to better optimize your Goitre shopping experience:

1. Compare - without doubt the biggest advantage that the Goitre offers shoppers today is the ability to compare thousands of Goitre at a time. This is a great thing, but not necessarily all the time! Too much can be daunting at times so take advantage of the great comparison sites and where possible let them do the hard work for you.

2. Research - if it has been said it will be on the internet. Ignorance is no longer a justifiable reason for buying the wrong thing. Take the time to research in detail everything that you could possible want to know about

3. Testimonials - don't know anybody that has bought a Goitre? Wrong! If the Goitre is good the internet will let you know. Use the Internet as a friend and get testimonials before you buy.

4. Questions - Got a question about Goitre then search the Forums, FAQ's, Blogs etc. Don't be afraid to ask .....

5. Reputation - Never heard of the company selling Goitre? Don't worry, no reason why you should know every company in the world, but you know someone that does! Use the internet to find out what people are saying about Goitre and build up a picture of their reputation for sales, returns, customer service, delivery etc.

6. Returns - still worried that even after all of the above your Goitre wont be what you want? Check out the returns policy. There is so much competition now that someone, somewhere is bound to offer the terms that you are comfortable with.

7. Feedback - happy with your Goitre then let people know, after all you are depending on others people input in your buying decision, so why not give a little back.

8. Security - check for the yellow padlock on the Goitre site before you buy, and the s after http:/ /i.e. https:// = a secure site

9. Contact - got a question about Goitre, or want to leave a comment then check out the sites contact page. Reputable companies have them and respond.

10. Payment - ready to pay for your Goitre, then use your credit card or PayPal! Be aware of companies that don't accept them, there may be genuine reasons but given the huge amount of choice you have when buying online there is no reason at all not to buy via credit card or PayPal.

{{Infobox_Disease | Name = {{PAGENAME--> | Image = Kone_med_stor_struma.jpg | Caption = a woman with a goitre | DiseasesDB = 5332 | ICD10 = {{ICD10|E|01|0|e|00-->-{{ICD10|E|01|2|e|00--> | ICD9 = {{ICD9|240.9--> | ICDO = | OMIM = | MedlinePlus = 001178 | eMedicineSubj = | eMedicineTopic = | MeshID = Goiter | -->A goitre (BrE), or goiter (AmE) (Latin struma), also called a bronchocele, is a swelling in the neck (just below Adam's apple or larynx) due to an enlarged thyroid.

Classification They are classified in different ways:

A "diffuse goitre" is a goitre that has spread through all of the thyroid (and can be a "simple goitre", or a "multinodular goitre").
"Toxic goitre" refers to goitre with hyperthyroidism. These most commonly due to Graves disease, but can be caused by inflammation or a multinodular goitre.
"Nontoxic goitre" (associated with normal or low thyroid levels) refers to all other types (such as that caused by lithium or certain other autoimmune diseases).

Causes Other causes are:

Hashimoto's thyroiditis (E06.3)
Graves-Basedow disease (E05.0)
inborn errors of thyroid hormone synthesis, causing congenital hypothyroidism (E03.0)
Thyroiditis (acute, chronic) (E06)
Adverse drug reaction of pharmacological therapy (E03.2)
Thyroid cancer
Iodine deficiency

Occurrence Iodine is necessary for the synthesis of the thyroid hormones triiodothyronine and thyroxine (T3 and T4). In conditions producing endemic goitre, when iodine is not available, these hormones cannot be made. In response to low thyroid hormones, the pituitary gland releases thyroid stimulating hormone (TSH). Thyroid stimulating hormone acts to increase synthesis of T3 and T4, but it also causes the thyroid gland to grow in size by increasing cell division.

Goitre is more common among women, but this includes the many types of goitre caused by autoimmune problems, and not only those caused by simple lack of iodine.

Treatment Treatment for goitre may not be necessary if the goitre is small. Hypothyroidism should be treated, and this treatment often leads to a substantial reduction in the size of the goitre. Removal of the goitre may be necessary if it causes difficulty with breathing or swallowing. There is now an alternative to surgery in large goitres. Radioiodine therapy with or without the pre-injection of a synthetic thyroid stimulating hormone, TSH, can relieve obstruction and reduce the size of the goitre by 30-65%. But removal of a goitre requires removing the thyroid. The complete removal of the thyroid gland removes the body's ability to produce thyroid hormone. In this case, oral thyroxine supplements are necessary to avoid harm from hypothyroidism.

History and future Paracelsus (born Philippus Aureolus Theophrastus Bombastus von Hohenheim) (1493–1541) was the first to describe the connection between goitre and the consumption of minerals, specifically lead in drinking water. "Paracelsus" entry in Dictionary.com, retrieved October 9, 2007

Goitre was previously common in many areas that were deficient in iodine in the soil. For example, in the English Midlands, the condition was known as Derbyshire Neck. In the United States, goitre was found in the Great Lakes, Midwestern United States, and Intermountain regions. The condition now is practically absent in affluent nations, where Sodium chloride is Iodized salt. However, it is still prevalent in India, "In Raising the World’s I.Q., the Secret’s in the Salt", article by Donald G. McNeil, Jr., December 16, 2006, New York Times Central Asia and Central Africa.

Some health workers fear that a resurgence of goitre might occur because of the trend to use rock salt and/or sea salt, which has not been fortified with iodine.

New research indicates that there may in fact be a tendency to inherit an increased vulnerability to goitre.

Famous goitre sufferers

President George H. W. Bush and his wife Barbara Bush (First Lady) both were diagnosed with Graves disease and enlarged thyroid glands, within 2 years of each other. In the president's case, the disease caused hyperthyroidism and cardiac arrythmia The Health and Medical History of President George Bush DoctorZebra.com. 8 August 2004. Retrieved 8 October 2006.
Andrea True
Kim Il-sung